10,071 research outputs found

    PIN21 ECONOMICAL EVALUATION OF ETRAVIRINE IN TREATMENT-EXPERIENCED HIV-1-INFECTED PATIENTS BASED ON DUET TRIALS

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    The electromagnetic component of albedo from superhigh energy cascades in dense media

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    Albedo from cascades induced in iron by high energy gamma quanta were Monte Carlo simulated. Thereafter the albedo electromagnetic component from proton induced cascades were calculated analytically. The calculations showed that the albedo electromagnetic component increases more rapidly than the nuclear active component and will dominate at sufficiently high energies

    Effective forms of participation of universities in development of a aditional education

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    В настоящее время очевидна необходимость применения сетевых форм в работе по развитию дополнительного образования. В статье приводится информация о формах участия вузов как заказчиков будущих мотивированных абитуриентов в работе по развитию системы дополнительного образования детей.Network forms of management in the work on the development of additional education are required. The article provides information about the forms of participation of universities in the work of the development of additional education

    More than colour attraction: behavioural functions of flower patterns

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    ReviewFlower patterns are thought to influence foraging decisions of insect pollinators. However, the resolution of insect compound eyes is poor. Insects perceive flower patterns only from short distances when they initiate landing or search for reward on the flower. From further away flower displays jointly form largersized patterns within the visual scene that will guide an insect’s flight behaviour. Chromatic and achromatic cues in such patterns may help insects to find, approach and learn rewarded locations in a flower patch, bringing them close enough to individual flowers. Flight trajectories and the spatial resolution of chromatic and achromatic vision in insects determine the effectiveness of floral displays, and both need to be considered in studies of plant-pollinator communication.BBSR

    Detection of fruit and the selection of primate visual pigments for color vision

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    Primates have X chromosome genes for cone photopigments with sensitivity maxima from 535 to 562 nm. Old World monkeys and apes (catarrhines) and the New World (platyrrhine) genus Alouatta have separate genes for 535-nm (medium wavelength; M) and 562-nm (long wavelength; L) pigments. These pigments, together with a 425-nm (short wavelength) pigment, permit trichromatic color vision. Other platyrrhines and prosimians have a single X chromosome gene but often with alleles for two or three M/L photopigments. Consequently, heterozygote females are trichromats, but males and homozygote females are dichromats. The criteria that affect the evolution of M/L alleles and maintain genetic polymorphism remain a puzzle, but selection for finding food may be important. We compare different types of color vision for detecting more than 100 plant species consumed by tamarins (Saguinus spp.) in Peru. There is evidence that both frequency-dependent selection on homozygotes and heterozygote advantage favor M/L polymorphism and that trichromatic color vision is most advantageous in dim light. Also, whereas the 562-nm allele is present in all species, the occurrence of 535- to 556-nm alleles varies between species. This variation probably arises because trichromatic color vision favors widely separated pigments and equal frequencies of 535/543- and 562-nm alleles, whereas in dichromats, long-wavelength pigment alleles are fitter

    PCV67 COST-EFFECTIVENESS OF FONDAPARINUX VS. ENOXAPARIN IN NON-ST-ELEVATION ACUTE CORONARY SYNDROMES IN RUSSIA

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    Functional interplay between chromatin remodeling complexes RSC, SWI/SNF and ISWI in regulation of yeast heat shock genes

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    Chromatin remodeling is an essential part of transcription initiation. We show that at heat shock gene promoters functional interactions between individual ATP-dependent chromatin remodeling complexes play critical role in both nucleosome displacement and Pol II recruitment. Using HSP12, HSP82 and SSA4 gene promoters as reporters, we demonstrated that while inactivation of SNF2, a critical ATPase of the SWI/SNF complex, primarily affects the HSP12 promoter, depletion of STH1- a SNF2 homolog from the RSC complex reduces histone displacement and abolishes the Pol II recruitment at all three promoters. From these results, we conclude that redundancy between SWI/SNF and RSC complexes is only partial and likely is affecting different chromatin remodeling steps. While inactivation of other individual ATP-dependent chromatin remodeling complexes negligibly affects reporter promoters, combinatorial inactivation of SNF2 and ISW1 has a synergistic effect by diminishing histone loss during heat induction and eliminating Pol II recruitment. Importantly, it also eliminates preloading of HSF on HSP82 and SSA4 promoters before heat shock and diminishes HSF binding during heat shock. These observations suggest that prior action of chromatin remodeling complexes is necessary for the activator binding

    Basket of Growth: New Export Industries in Sverdlovsk Region

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    The authors examine an export basket and reveal the new export goods for Sverdlovsk region, which might be used to transform the productive structure and upgrade export of the region. For each product, in which the region might develop its comparative advantage, the authors develop a measure of efforts, which are supposed to be made to include this good into the export basket, and a measure of the income level for the product. As a result the authors get a cluster of new and the most attractive export goods. Special methodology is used to choose the best cities to allocate the production of the new export goods.Export goods, comparative advantages, industrial cluster, production allocation

    Collision damping in the pi 3He -> d'N reaction near the threshold

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    We present a simple quantum mechanical model exploiting the optical potential approach for the description of collision damping in the reaction pi 3He -> d'N near the threshold, which recently has been measured at TRIUMF. The influence of the open d'N -> NNN channel is taken into account. It leads to a suppression factor of about ten in the d' survival probability. Applications of the method to other reactions are outlined.Comment: RevTeX4, 14 pages, 3 Postscript figures, uses epsfig.sty, to appear in Phys.Rev.
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